Intrinsic Control for Genome and Transcriptome Editing in Communities (InCoGenTEC)

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Secure bioscience design project expands CRISPR molecular toolkit

News Article, January 17, 2023 • The Intrinsic Control for Genome and Transcriptome Editing in Communities (InCoGenTEC) project team, exploiting the CRISPR-associated (CRISPR-Cas) system in bacteria, developed a novel variant of the Cas13 enzyme by fusing it to translation Initiation Factor IF3, enhancing protein expression 21.3-fold above Cas13 alone. InCoGenTEC, led by NTESS for DOE’s Biological...