Publications

Slaughter, Brandon V.; Lino, Christopher A.; McBride, Amber A.; Fleig, Patrick F.; Conroy, Marissa A.; Melo, Claire F.; Wilkinson, Brian S.; Garcia, Gabriel G.; Wu, Terry H.; Adolphi, Natalie L.; Reed, Scott T.; Ashley, Carol S.; Brinker, C.J.; Carnes, Eric C.; Ashley, Carlee E.

Abstract not provided.

Schwarz, Jens S.; Rambo, Patrick K.; Smith, Ian C.; Ashley, Carol S.; Reed, Scott T.; Johnson, William Arthur.

Abstract not provided.

Rambo, Patrick K.; Schwarz, Jens S.; Smith, Ian C.; Ashley, Carol S.; Branson, Eric D.; Dunphy, Darren R.; Cook, Adam W.; Reed, Scott T.; Johnson, William Arthur.

In order to develop the next generation of high peak intensity lasers, new grating technology providing higher damage thresholds and large apertures is required. The current assumption is that this technical innovation will be multilayer dielectric gratings, wherein the uppermost layer of a thin film mirror is etched to create the desired binary phase grating. A variant of this is explored with the upper grating layer being a lower density gelatin-based volume phase grating in either sol-gel or dichromated gelatin. One key benefit is the elimination of the etching step.

Singh, Anup K.; Schmitt, Randal L.; Johnson, Mark S.; Hargis, Philip J.; Simonson, Robert J.; Simonson, Robert J.; Schoeniger, Joseph S.; Ashley, Carol S.; Brinker, C.J.; Hance, Bradley G.

This report summarizes the development of sensor particles for remote detection of trace chemical analytes over broad areas, e.g residual trinitrotoluene from buried landmines or other unexploded ordnance (UXO). We also describe the potential of the sensor particle approach for the detection of chemical warfare (CW) agents. The primary goal of this work has been the development of sensor particles that incorporate sample preconcentration, analyte molecular recognition, chemical signal amplification, and fluorescence signal transduction within a ''grain of sand''. Two approaches for particle-based chemical-to-fluorescence signal transduction are described: (1) enzyme-amplified immunoassays using biocompatible inorganic encapsulants, and (2) oxidative quenching of a unique fluorescent polymer by TNT.