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Rapid fluorescence-activated cell sorting with optical-force deflection in a microfluidic device

Perroud, Thomas D.; Patel, Kamlesh P.

We present our initial results on the integration of a fluorescence- activated cell sorter into a microfluidic platform for the study of macrophages. We show that hydrodynamically focused macrophages can be efficiently sorted into another laminar flow by optical-force deflection, similar to optical tweezers. Although high laser power is required for sorting macrophages, initial observations show no obvious laser damage to the cells. © 2006 Society for Chemistry and Micro-Nano Systems.