Publications

Integrated microfluidic hub for automated prepration of dna libraries for personalized sequencing systems

Jebrail, Mais J.; Kim, Hanyoup; Thaitrong, Numrin T.; Bartsch, Michael B.; Renzi, Ronald F.; Patel, Kamlesh D.

While DNA sequencing technology is advancing at an unprecedented rate, sample preparation technology still relies primarily on manual bench-top processes, which often can be slow, labor-intensive, inefficient, or inconsistent. To address these disadvantages, we developed an integrated microfluidic platform for automated preparation of DNA libraries for next generation sequencing. This sample-to-answer system has great potential for rapid characterization of novel and emerging pathogens from clinical samples.