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Diffusion-based free solution DNA hybridization and transport in a nanofluidic device

Pennathur, Sumita P.; Huber, David; Rhieu, Steve; Patel, Kamlesh D.

We report numerical, and experimental studies of diffusion-based, free-solution hybridization of nucleic acids in a nanofluidic device. We present continuum-based models for transport of oligonucleotides in a nanofluidic T-junction serpentine channel. © 2006 Society for Chemistry and Micro-Nano Systems.