Pulse Sequences

This page provides some of the NMR pulse sequences that were developed, or heavily modified at Sandia National Laboratories. Additionally included are some reference experiments for making comparisons.

Warning These pulse sequences are provided only as a guide for experienced users to implement with due care. They may contain mistakes. Improper setting of parameters may cause damage to the spectrometer, probe, or sample. All protections have been removed! The authors nor their employers accept any responsibility for use of these experiment. Any copy or modification of these sequences should contain the header in each file.

SCRAM

Swept Compensated Refocusing for Arbitrary Modulation (SCRAM) is a dual channel broadband inversion pulse block. SCRAM enables arbitrary and independent evolution of I-spin chemical shift, S-spin chemical shift and IS spin-spin coupling. As a result SCRAM can be used to build broadband version of many heteronuclear correlation experiments.

Reference

Brennan J. Walder, Josefine D. McBrayer, Katharine L. Harrison, and Keith J. Fritzsching “Multipurpose Broadband NMR Inversion Sequences” J. Phys. Chem. A. (2023) https://doi.org/10.1021/acs.jpca.3c02445

All Sequences

You can download our whole library of SCRAM based sequences, along with a few traditional hard pulse sequences that can be used to make comparisons .

All SCRAM SequencesDownload

Individual Sequences

HSQC Experiments

SCRAM-HSQCDownload

2D HSQC with 3 SCRAM blocks

SCRAM-HSQC-GPDownload

2D HSQC with 3 SCRAM blocks and gradient pulses

Edited SCRAM-HSQC-GPDownload

2D Multiplicity Edited HSQC with 3 SCRAM blocks and gradient pulses

Lightweight SCRAM-HSQC-GPDownload

2D HSQC using 3 lightweight SCRAM blocks and gradient pulses for use with smaller coupling values and shorter pulses.

HMQC Experiments

SRAM-HMQCDownload

2D HMQC using 1 SCRAM block

SCRAM-HMQC-GPDownload

2D HMQC using 1 SCRAM block and gradient pulses

J-resolved Experiments

SCRAM-J-resolved Z2Download

2D J-resolved using 3 SCRAM blocks, that gives Z2 multiplets in the indirect dimension.

SCRAM-J-resolved-GP Z2Download

2D J-resolved using 3 SCRAM blocks with gradient pulses, that gives Z2 multiplets in the indirect dimension.

INEPT Experiments

SCRAM-INEPT Z1_Download

1D INEPT using 1 SCRAM block

SRAM-INEPT Z0Download

1D INEPT+ using 2 SCRAM blocks